Yet another study praising the glories of one of the major components of coffee.
The study (conducted by Chen, Gawryluk, Wagener, Ghribi, and Geiger of UND) was published online ahead of print on April 3, 2008; it presents results from humans and animals support the argument that the investigators…
“…found that caffeine blocked high cholesterol diet-induced increases in extravasation of IgG and fibrinogen, increases in leakage of Evan’s blue dye, decreases in levels of the tight junction proteins occludin and ZO-1, increases in astrocytes activation and microglia density where IgG extravasation was present. Chronic ingestion of caffeine protects against high cholesterol diet-induced increases in disruptions of the BBB, and caffeine and drugs similar to caffeine might be useful in the treatment of Alzheimer’s disease.“
- The news: http://news.bbc.co.uk/2/hi/health/7326839.stm
- The article (may require institutional access): http://www.jneuroinflammation.com/content/5/1/12
- The journal in PubMed central: http://www.pubmedcentral.nih.gov/tocrender.fcgi?journal=249
This appears to be “kind of a big deal…“